Volume 1

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Review Article

Sweet Taste Drinks Effects on Reducing Injection Pain and Associated Stress among Infants: A Meta-Analysis of Randomized Controlled Trials

Manal Kassab, Jasim Anabrees*, Denise Harrison, Wadah Khriesat, Shaolin Chen

Administration of oral sweet tasting drinks, with and without non-nutritive sucking reduces injection pain in newborn neonates. It is less certain if analgesic effects exist for infants’ beyond the neonatal period, and up to one year of age. This is an update of the review, Sweet-tasting solutions for needle-related procedural pain in infants one month to one year of age.

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Research Article

Evaluation of Predictive Models to Identify Low Risk Fever and Neutropenia in Children with Cancer

Keren Glinert Muller, Sarah Worley, Aron Flagg, Johanna Goldfarb*

Children with fever and neutropenia (FN) are urgently treated with empiric intravenous antibiotics, although most have no proven bacterial infection. A robust model to identify children at low risk for severe infection might allow less aggressive therapy or decreased length of hospital stay. Multiple risk stratification models have been developed with numerous predictive variables, but no model is standard. We conducted a retrospective chart review of FN episodes from pediatric cancer patients from 2005-2013 to develop and validate predictive models to identify children at low risk for severe infection.

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