Articles in Press

Volume 1



Case Report

Hyperreactio Luteinalis after Pregnancy with Severe Twin-to-Twin Transfusion Syndrome: A Case Report

Tikvica Luetić Ana, MD, PhD*, Habek Dubravko, MD, PhD, Nikolina Soken, MD

Hyperreactio luteinalis (HL) is a rare condition of bilateral cystic ovarian enlargement that usually develops in twin and molar pregnancies. Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic twin pregnancies due to the pathological vascular anastomoses that often results with perinatal loss and serious morbidity. We present a case of patient with pregnancy loss due to the severe TTTS that later developed HL with complications of ascites and pleural effusion requiring active treatment.

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Research Article

Progestin Intrauterine Device versus Intramuscular Medroxyprogesterone Acetate for Heavy Menstrual Bleeding Control

Oroma B. Nwanodi, MD*, Locum Tenen

Up to 30% of women will have heavy menstrual bleeding (HMB), leading to 20% of gynecology visits. HMB impairs women’s quality of life. As 80% of HMB cases have normal anatomy, generally, surgery is clinically excessive, cost-ineffective treatment. Both intramuscular medroxyprogesterone acetate (DMPA) and the 5-year, 52 mg, levonorgestrel intrauterine device (5yr-IUD) are known for potential amenorrhea. Weight gain is a known adverse effect of DMPA. Astute patients also question the 5yr-IUD’s weight gain potential. Therefore, the comparative efficacy of DMPA and 5yr-IUD for menstrual control and the associated weight gain need clarification.

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Research Article

A Descriptive Study of the Cancer Risk Assessment Process for BRCA 1/2 in Women with Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in the Hamilton-Brant-Haldimand-Wentworth Local Health Integrated Network (LHIN)

Amber Murphy, Laurie Elit*, Kathleen Bell, Greg Pond, Holger Hirte, Waldo Jimenez, Lua Eirikkson, Clara Reade, Mona Lisa Sur, Louise Bordeleau

In 2015 nearly 3000 women were diagnosed with ovarian cancer in Ontario, Canada and approximately two thirds of the affected population died from their disease3. Globally, epithelial ovarian cancer (EOC) has the highest mortality rate of all gynecologic malignancies, And serous EOC accounts for nearly 80% of ovarian cancer deaths.

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